Journal of Organic Chemistry
Journal of Organic Chemistry
5 years ago

Radical Decarboxylation/Annulation of Acrylamides with Aliphatic Acyl Peroxides

Radical Decarboxylation/Annulation of Acrylamides with Aliphatic Acyl Peroxides
Changduo Pan, Qingting Ni, Jin-Tao Yu, Yu Fu
A radical decarboxylation/annulation of acrylamides with aliphatic acyl peroxides was developed, giving a series of linear alkylated oxindoles in moderate to good yields. The reaction used aliphatic acyl peroxides as the linear alkyl radical source and tolerated a broad scope of substrates under metal-free conditions, offering a simple and efficient approach toward alkylated oxindoles.

Publisher URL: http://dx.doi.org/10.1021/acs.joc.7b00663

DOI: 10.1021/acs.joc.7b00663

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.