Nuclear Pore Protein Meets Transcription Factor in Neural Fate
How nuclear architecture contributes to transcriptional regulation in neural progenitor cells (NeuPCs) is poorly understood. A study by Toda et al. (2017) now shows that the nuclear pore protein Nup153 associates with the Sox2 transcription factor in the regulation of NeuPC maintenance and neural fate.
Publisher URL: http://www.cell.com/neuron/fulltext/S0896-6273(17)30928-5
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