4 years ago

Withholding Versus Continuing Angiotensin-Converting Enzyme Inhibitors or Angiotensin II Receptor Blockers Before Noncardiac Surgery: An Analysis of the Vascular Events in Noncardiac Surgery Patients Cohort Evaluation Prospective Cohort

Devereaux, B., Thompson, A., Devereaux, P. J., Duceppe, E., Rochwerg, B., Punthakee, Z., Spencer, F. A., Borges, F. K., Sanders, R. D., Belley-Côté, E. P., Paul, J., Salehian, O., Roshanov, P. S., Sessler, D. I., Raymer, K. E., Koshy, M., Guyatt, G. H., Patel, A., Worster, A., Le Manach, Y., Sloan, E. N., Tandon, V., Morley, E. E.
(Abstracted from Anesthesiology, 126(1):16–27, 2017) The purpose of this international prospective cohort study was to assess the effect of withholding angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) on the risk of 30-day composite outcome of all-cause death, myocardial injury following noncardiac surgery (MINS), and stroke, as well as to determine the relationship between withholding ACEIs/ARBs and perioperative hypotension.
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