5 years ago

Development of a safe and scalable route towards a tau PET tracer precursor

Development of a safe and scalable route towards a tau PET tracer precursor
A scalable 5-step synthesis of the diazacarbazole derivative 1 used as tau PET tracer precursor is reported. Key features of this synthesis include a Buchwald-Hartwig amination, a Pd catalyzed C-H activation and a Suzuki-Miyaura cross-coupling.

Publisher URL: www.sciencedirect.com/science

DOI: S0968089617313822

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