5 years ago

Preparation of Hydrophilic Blood Compatible Polypropylene/Pluronics F127 Films

Mohamad Hossein Moghadasi, Mahsa Hakani, Vahid Haddadi-Asl, Seyed Shahrooz Zargarian
In order to improve surface hydrophilicity, blood compatibility and cell-anti adhesion of Polypropylene (PP) film, PPO-PEO-PPO used as macromolecular surface modifier through physical blending. Surface properties of blended PP/PF127 samples were investigated by attenuated total reflection infrared spectroscopy (ATR-FTIR) and water contact angle (WCA) measurements. Results demonstrated that pluronic F127 migrated to the surface. Thus, mechanical properties of blended PP/PF127 samples with the aim of the revealing the effects of the presence of modifier in the bulk were investigated through Differential Scanning Calorimetry (DSC), X-ray diffraction (XRD) and tensile tests. The biocompatibility and hemocompatibility of modified PP films were evaluated by MTT assay, platelet-rich plasma and hemolysis tests. These results showed excellent anti-cell and anti-platelet adhesion which deems the prepared blended films proper biomaterials. This article is protected by copyright. All rights reserved.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/jbm.a.36269

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