4 years ago

Relationship between neighbourhood socioeconomic status and venous thromboembolism: Results from a population-based study

D. Kort, N. van Rein, H. W Vermaas, S.C. Cannegieter, F.J.M van der Meer, N. Wiersma, W.M. Lijfering
Background The association between socioeconomic status and arterial cardiovascular disease is well established. However, despite its high burden of disability-adjusted life years, little research has been done to determine whether socioeconomic status is associated with venous thromboembolism. Objective To determine if neighbourhood socioeconomic status is associated with venous thromboembolism in a population-based study from the Netherlands. Methods We identified all patients aged 15 years and older with a first event of venous thromboembolism from inhabitants who lived in the urban districts of The Hague, Leiden and Utrecht in the Netherlands in 2008-2012. Neighbourhood socioeconomic status was based on the status score which combines educational level, income and unemployment on a 4-digit postal code level. Incidence rate ratios of venous thromboembolism were calculated for different levels of neighbourhood socioeconomic status, with adjustments for age and sex. Results 7373 patients with a first venous thromboembolism (median age 61 years, 50% deep vein thrombosis) were identified among more than 1.4 million inhabitants. Higher neighbourhood SES was associated with lower incidence of VTE. In the two highest status score groups (i.e. the 95-99th and >99th percentile), the adjusted incidence rate ratios were 0.91 (95% CI 0.84-1.00) and 0.80 (95% CI 0.69-0.93) respectively, compared with the reference status score group (i.e. 30-70th percentile). Conclusions High neighbourhood socioeconomic status is associated with a lower risk of first venous thromboembolism.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1111/jth.13868

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