Synthesis, Biological Evaluation and Structure-Activity Relationship of 2-Phenylaminomethylene-cyclohexane-1,3-diones as Specific Anti-tuberculosis Agents

5 years ago

Synthesis, Biological Evaluation and Structure-Activity Relationship of 2-Phenylaminomethylene-cyclohexane-1,3-diones as Specific Anti-tuberculosis Agents

syed khalid Yousuf, Mohd Jamal Dar Dar, Bashir Ahmad Shairgojray, Zubair Shanib Bhat, bilal ahmad bhat, Shajrul Amin, Paramjeet singh singh, Muzafar Rather, Zahoor Ahmad Parry, Bisma Teli, Mubashir Maqbool, ALI MOHD LONE

The present study utilised whole cell based phenotypic screening of thousands of diverse small molecules against Mycobacterium tuberculosis H37Rv (M.tb.) and identified cyclohexane-1,3-dione based structures 5 and 6 as hits....

Publisher URL: http://feeds.rsc.org/~r/rss/MD/~3/UCdOtK3Jpxk/C7MD00350A

DOI: 2017/MD/C7MD00350A

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