3 years ago

Nanocarriers: Capturing “Extraordinary” Soft-Assembled Charge-Like Polypeptides as a Strategy for Nanocarrier Design (Adv. Mater. 39/2017)

Nanocarriers: Capturing “Extraordinary” Soft-Assembled Charge-Like Polypeptides as a Strategy for Nanocarrier Design (Adv. Mater. 39/2017)
María J. Vicent, Juan J. Arroyo-Crespo, Amaya Niño-Pariente, Lorenzo Albertazzi, Ana Armiñán, Vicent J. Nebot, Alison Paul, Aroa Duro-Castano, Natalia Feiner-Gracia
A novel strategy developed by Vicent J. Nebot, María J. Vicent, and co-workers in article number 1702888 to produce nanosized drug carriers may improve the anticancer drug activity of polymer therapeutics and patient treatment. The discovery of an attractive force between negatively charged star-shaped-polypeptides allows single stars to self-assemble into unprecedented larger spherical structures with enhanced pharmacokinetic characteristics. Furthermore, selective lymph-node accumulation of these carriers may lead to applications in anti-metastatic and immunotherapeutic strategies.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/adma.201770280

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