Tropical rainforests, naturally resistant to fire when intact, are increasingly vulnerable to burning due to ongoing forest perturbation and, possibly, climatic changes. Industrial-scale forest degradation and conversion are increasing fire occurrence, and interactions with climate anomalies such as El Niño induced droughts can magnify the extent and severity of fire activity. The influences of these factors on fire frequency in tropical forests has not been widely studied at large spatio-temporal scales at which feedbacks between fire reoccurrence and forest degradation may develop. Linkages between fire activity, industrial land use, and El Niño rainfall deficits are acute in Borneo, where the greatest tropical fire events in recorded history have apparently occurred in recent decades. Here we investigate how fire frequency in Borneo has been influenced by industrial-scale agricultural development and logging during El Niño periods by integrating long-term satellite observations between 1982 and 2010 – a period encompassing the onset, development, and consolidation of its Borneo’s industrial forestry and agricultural operations as well as the full diversity of El Niño events. We record changes in fire frequency over this period by deriving the longest and most comprehensive spatio-temporal record of fire activity across Borneo using AVHRR Global Area Coverage (GAC) satellite data. Monthly fire frequency was derived from these data and modelled at 0.04° resolution via a random-forest model, which explained 56% of the monthly variation as a function of oil palm and timber plantation extent and proximity, logging intensity and proximity, human settlement, climate, forest and peatland condition, and time, observed using Landsat and similar satellite data. Oil-palm extent increased fire frequency until covering 20% of a grid cell, signalling the significant influence of early stages of plantation establishment. Heighted fire frequency was particularly acute within 10km of oil palm, where both expanding plantation and smallholder agriculture are believed to be contributing factors. Fire frequency increased abruptly and dramatically when rainfall fell below 200mmmonth−1, especially as landscape perturbation increased (indicated by vegetation index data). Logging intensity had a negligible influence on fire frequency, including on peatlands, suggesting a more complex response of logged forest to burning than appreciated. Over time, the epicentres of high-frequency fires expanded from East Kalimantan (1980’s) to Central and West Kalimantan (1990’s), coincidentally but apparently slightly preceding oil-palm expansion, and high-frequency fires then waned in East Kalimantan and occurred only in Central and West Kalimantan (2000’s). After accounting for land-cover changes and climate, our model under-estimates observed fire frequency during ca. 1990–2002 and over-estimates it thereafter, suggesting that a multi-decadal shift to industrial forest conversion and forest landscapes may have diminished the propensity for high-frequency fires in much of this globally significant tropical region since ca. 2000.