4 years ago

Synthesis of Spirocyclic Pyrrolidines: Advanced Building Blocks for Drug Discovery

Synthesis of Spirocyclic Pyrrolidines: Advanced Building Blocks for Drug Discovery
Oksana O. Yanshyna, Pavel K. Mykhailiuk, Konstantin S. Gavrilenko, Tetiana V. Druzhenko, Maryna V. Butko, Bohdan A. Chalyk
Invited for the cover of this issue is the group of Pavel K. Mykhailiuk at the Taras Shevchenko National University of Kyiv and Enamine Ltd. The image depicts spirocyclic pyrrolidine—a novel building block for drug discovery. Read the full text of the article at 10.1002/chem.201702362. “…we were very much impressed by the high practical potential of the developed procedure: from every cyclic ketone, a variety of spirocyclic pyrrolidines can be obtained.” Read more about the story behind the cover in the Cover Profile and about the research itself on page ▪▪ ff. (DOI: 10.1002/chem.201702362).

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/chem.201704330

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