ACS Nano
ACS Nano
5 years ago

A Simple, Cleated DNA Walker That Hangs on to Surfaces

A Simple, Cleated DNA Walker That Hangs on to Surfaces
Cheulhee Jung, Andrew D. Ellington, Peter B. Allen
We designed and demonstrated a single-legged or unipedal walker that has a “cleat” that allows it to persistently associate with a track and make autonomous decisions about movement. The walker is highly processive over long periods of time, as shown by its movement over a microparticle surface suffused with substrate. The simple design can be readily optimized on the basis of simple energetic considerations. The walker can be used for signal amplification and should prove especially valuable for programming amorphous computations within chemical reaction networks.

Publisher URL: http://dx.doi.org/10.1021/acsnano.7b02693

DOI: 10.1021/acsnano.7b02693

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