3 years ago

Pro: Steroids can be withdrawn posttransplant in recipients with autoimmune hepatitis

James R. Burton, Lisa Forman, Avash Kalra

Abstract

Corticosteroids have been a mainstay of immunosuppression following liver transplantation. However, evolution in the field of transplant immunology has produced steroid‐free options, resulting in most transplant centers weaning steroids post‐transplant within days to months – an evidence‐based management decision. Patients with autoimmune hepatitis, however, receive corticosteroids prior to transplant. This raises the question of whether these patients should also be weaned from corticosteroids. In this review, we discuss the benefits of avoiding steroid use in this population of patients – an approach that not only avoids the adverse effects of corticosteroids, but does so without risking graft failure from recurrent autoimmune hepatitis or from acute cellular rejection. This article is protected by copyright. All rights reserved.

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.