Scientific Reports
Scientific Reports
5 years ago

Use of PIXE/PIGE for sequential Ca and F measurements in root carious model

T. Nakano, K. Yagi, K. Okuyama, H. Yamamoto, T. Ishimoto, Y. Matsuda, M. Hayashi, R. Uemura
The progress of caries has conventionally been evaluated by checking changes in mineral density using transverse microradiography (TMR). Recent advances have seen development of a new measurement system, using in-air micro proton induced X-ray/gamma-ray emission (PIXE/PIGE). PIXE/PIGE enables analysis of distributions and concentrations of multiple mineral elements in a carious lesion. The aim of this study was to evaluate the effectiveness of PIXE/PIGE for investigating the development of root caries. In summary, we successfully established a multi-elemental sequential measuring method using in-air micro-PIXE/PIGE to identify the dynamic distributions and concentrations of Ca and F in human root dentin. The PIXE/PIGE potentially offers a useful advantageous technique for studying carious development by using as a combination with conventional techniques such as TMR and Micro-computed tomography (µCT).

Publisher URL: https://www.nature.com/articles/s41598-017-14041-4

DOI: 10.1038/s41598-017-14041-4

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