3 years ago

Exercise training may improve the tumour microenvironment after breast cancer (PEDro synthesis)

Meneses-Echavez JF, Correa-Bautista JE, Gonzalez-Jimenez E, et al. Cancer Epidemiol Biomarkers Prev. 2016;25:1009–17.

Background

Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer deaths in women worldwide.1 Many studies show a relationship between exercise behaviour and breast cancer prognosis. Additionally, more recent research reports a relationship between fitness and disease-free survival in women with breast cancer.2 However, there is paucity of evidence exploring the various mechanisms underlying the exercise-prognosis relationship in cancer. This systematic review addressed one possible mechanism: the effect of exercise training on inflammatory mediators.

Aim

This systematic review aimed to quantitatively analyse the effect of exercise training on inflammatory biomarkers in breast cancer survivors.

Searches and inclusion criteria

PubMed, CENTRAL, Embase and Scopus were searched with search terms related to breast cancer, exercise and inflammatory mediators. In addition, six relevant journals and...

Publisher URL: http://bjsm.bmj.com/cgi/content/short/51/21/1564

DOI: 10.1136/bjsports-2016-097235

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