3 years ago

Asymmetric detrended fluctuation analysis in neonatal stress

Objective : To detect stress in newborns by observing heart rate (HR) variability utilizing an asymmetric detrended fluctuation analysis (ADFA), we sought to determine the fractal structure of the series of inter-beat intervals, so as to distinguish the periods of acceleration of the HR from decelerations. Thus, two scaling exponents, α + and α − , representing decelerations and accelerations respectively, are obtained. Approach : Forty healthy term newborns were included in this study, undergoing two different types of stress stimuli: routine heel lance blood sampling for metabolic screening purposes, and its simulation by applying dull pressure on the heel. Main results : It appears that when newborns face stress, the scaling exponent related to accelerations significantly increases and becomes higher than the deceleration scaling exponent. To test the diagnostic properties of the scaling exponents, an ROC curve analysis wa...

Publisher URL: http://iopscience.iop.org/0967-3334/39/8/085006

DOI: 10.1088/1361-6579/aad425

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