Angewandte Chemie - International Edition
Angewandte Chemie - International Edition
4 years ago

Analytical Description of NMR Relaxation Highlights Correlated Dynamics in Intrinsically Disordered Proteins

Analytical Description of NMR Relaxation Highlights Correlated Dynamics in Intrinsically Disordered Proteins
Anton Abyzov, Nicola Salvi, Martin Blackledge
The potential energy landscapes of intrinsically disordered proteins are remarkably flat compared their folded counterparts, making their functional modes difficult to study. In their Communication (DOI: 10.1002/anie.201706740), M. Blackledge and co-workers use a combination of high-resolution NMR spectroscopy and advanced molecular dynamics simulation to investigate the extent of functionally important correlated motions in this essential class of proteins.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/anie.201710486

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