Angewandte Chemie - International Edition
Angewandte Chemie - International Edition
4 years ago

Asymmetric Intermolecular Heck Reaction of Propargylic Acetates and Cycloalkenes to Access Fused Cyclobutenes

Asymmetric Intermolecular Heck Reaction of Propargylic Acetates and Cycloalkenes to Access Fused Cyclobutenes
Jianrong Steve Zhou, Zhiwei Jiao, Qi Shi
An asymmetric Heck annulation of propargylic acetates with several types of cyclic olefins affords highly strained cyclobutenes in high enantioselectivity. An intermolecular Heck reaction between propargylic acetates and cyclic olefins results in the enantioselective synthesis of highly strained cyclobutenes.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/anie.201708435

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