3 years ago

Manipulation of Biomolecule-Modified Liquid-Metal Blobs

Manipulation of Biomolecule-Modified Liquid-Metal Blobs
Yue Yu, Eijiro Miyako
Soft and deformable liquid metals (LMs) are building components in various systems related to uncertain and dynamic task environments. Herein we describe the development of a biomolecule-triggered external-manipulation method involving LM conjugates for the construction of future innovative soft robotics operating in physiological environments. Functional soft hybrids composed of a liquid-metal droplet, a thiolated ligand, and proteins were synthesized for the expression of diverse macroscopic commands, such as attachment to cells, binary fusion, and self-propelled movement through molecular recognition and enzymatic reactions. Our technology could be used to create new state-of-the-art soft robots for chemical and biomedical engineering applications. No interest in blobbing out: Biomolecule-functionalized liquid-metal (LM) blobs (see picture) were developed with macroscopic behavior promoted by molecular recognition, for example, through formation of the biotin–avidin complex. Bubble formation on the surface of enzyme-modified LM conjugates also enabled self-propelled dynamic motion. These behaviors could lead to efficient LM soft robots for operation in physiological environments.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/anie.201705996

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