3 years ago

Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety

Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety
Iain J. Day, Supojjanee Sansook, John Spencer, Cory A. Ocasio, Jonathan M. Elkins, Oleg Fedorov, James M. Bennett, Simon J. Coles, Graham J. Tizzard
A series of 3-methylidene-1H-indol-2(3H)-ones substituted with a 5- or 6-pentafluorosulfanyl group has been synthesized by a Knoevenagel condensation reaction of SF5-substituted oxindoles with a range of aldehydes.

Publisher URL: http://feeds.rsc.org/~r/rss/OB/~3/klzHvS3XmjA/C7OB02289A

DOI: 2017/OB/C7OB02289A

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