3 years ago

Asymmetric acetate-Mannich reaction of chiral isatin derived ketimines and its applications

Atanu Hazra, Suhas Shivajirao Bhosale, Saumen Hajra
A highly efficient TMSOTf-mediated asymmetric acetate-Mannich reaction of isatin derived tert-butylsulfinyl ketimines and S-phenyl thioacetate was developed to afford the direct synthesis of indole-based [small beta]3,3-amino acid thioester with excellent selectivity...

Publisher URL: http://feeds.rsc.org/~r/rss/OB/~3/djihLHBch88/C7OB02407J

DOI: 2017/OB/C7OB02407J

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