3 years ago

Copper-Catalyzed Regioselective Synthesis of Multisubstituted Furans by Coupling between Ketones and Aromatic Olefins

Copper-Catalyzed Regioselective Synthesis of Multisubstituted Furans by Coupling between Ketones and Aromatic Olefins
Md Ashif Ali, Sourav Jana, Amrita Dey, Alakananda Hajra
A regioselective synthesis of multisubstituted furan derivatives has been developed via Cu(II)-catalyzed intermolecular annulation of aryl ketones with a wide range of aromatic olefins under ambient air in good yields. This protocol is applicable to both cyclic and acyclic aryl ketones.

Publisher URL: http://dx.doi.org/10.1021/acs.joc.7b00476

DOI: 10.1021/acs.joc.7b00476

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