4 years ago

One-step synthesis of functional pNR/rGO composite as a building block for enhanced ascorbic acid biosensing

One-step synthesis of functional pNR/rGO composite as a building block for enhanced ascorbic acid biosensing
An electrochemical sensor for ascorbic acid (AA) was prepared via an one-step electrochemical approach by reducing graphene oxide (rGO) and co-polymerizing neutral red (NR) and rGO to form a pNR/rGO hybrid film on the glassy carbon electrode (pNR/rGO-GCE). Structures and properties of the obtained pNR/rGO film were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared (FT-IR) and UV-vis techniques. A significant decrease of charge-transfer resistance (Rct) from over 20,000 Ω for pNR-GCE to 130 Ω for pNR/rGO-GCE was validated by electrochemical impedance spectroscopy (EIS) measurement. Particularly, electrochemical data revealed that pNR/rGO film could effectively enhance the electron transfer between AA and electrode, and thus reduce the overpotential of AA oxidation. Two linear regression areas with 0.05–0.75 mM and 0.9–24.9 mM, detection limit with 1.4 μM, and stability over 2 weeks were obtained. The coexisting distractions such as dopamine, uric acid and glucose were detected and eliminated. Moreover, the pNR/rGO-GCE gave the same determination results as that obtained with HPLC when measuring real samples, including vitamin C beverage and human serum.

Publisher URL: www.sciencedirect.com/science

DOI: S0003267017306888

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.