3 years ago

Imidazo[1,2-a]pyridin-6-yl-benzamide Analogs as Potent RAF Inhibitors

Imidazo[1,2-a]pyridin-6-yl-benzamide Analogs as Potent RAF Inhibitors
A series of imidazo[1,2-a]pyridin-6-yl-benzamide analogs was designed as inhibitors of B-RAFV600E. Medicinal chemistry techniques were employed to explore the SAR for this series and improve selectivity versus P38 and VEGFR2.

Publisher URL: www.sciencedirect.com/science

DOI: S0960894X17310429

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