3 years ago

Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses

Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses
Wadih Arap, Israel T da Silva, Diana N Nunes, Andre A Teixeira, Serena Marchiò, Richard L Sidman, Marc Barry, Emmanuel Dias-Neto, Ricardo J Giordano, Renata Pasqualini, Richard C Lauer, Bryce Chackerian, Webster K Cavenee, Cosette M Wheeler
The hypothesis is discussed that prostate cancer marker lncRNA PCA3 was introduced into the human genome by an oncogenic virus, and that viral infection-related mechanisms might underlie its overexpression and prostate cancer initiation and/or progression.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.15252/emmm.201708072

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