Join us this June for our three-part Researcher Live series on ‘Sleep & the Brain’! Tune in on 28th June at 9am GMT / 10am BST for the third episode together with Dr Laura Bojarskaite, University of Oslo. on the ‘Nightlife of the stars of the brain: Asdtrocyte Ca2+ signaling helps to maintain uninterrupted slow wave sleep’. Sign up here to receive notifications for this series.
What are we going to talk about in this episode?
While neuronal circuits are indisputably considered to be the computational integrators of behavior, a complete understanding of the nervous system must also incorporate the surrounding glial cells. Astroglial function is far beyond passive support of neuronal circuits. Astroglia inextricably influences neuronal physiology from early development through guidance and synaptic shaping, and through entire life by structural and trophic support, immune function and extracellular homeostasis. With such essential functions astroglia are consequential to many different behaviors in adult animals. Sleep is no exception. Sleep regulation has historically been admitted as a task exclusively for neurons. Changes in other types of brain cells, such as astrocytes, across the sleep-wake cycle and their role in sleep regulation are comparatively unexplored. Understanding what molecular mechanisms and signaling pathways astrocytes employ during sleep, and how they influence sleep physiology and brain rhythms, is a central outstanding question in the field of sleep research. In this talk, Laura will discuss our findings where astrocytic signaling was first described during natural sleep and showed that astrocytic activity during sleep is important to maintain uninterrupted slow wave sleep and to maintain proper brain rhythms during sleep, such as sleep spindles.
The slides for this event can be found here.
Please follow Researcher Live’s profile ‘Sleep & the Brain’ to receive updates for upcoming events!
- 15th June, 2pm GMT / 3pm BST - ‘Role of sleep in health and lifespan’ with Dr Alen Juginovic, Harvard Medical School – this event is sponsored by Annual Reviews!
- 21st June, 4pm GMT / 5pm BST - ‘Sleeping under the stars: astrocyte contributions to sleep’ Dr Ashley Ingiosi, Washington State University - ‘Sleeping under the stars: astrocyte contributions to sleep’ - this event is sponsored by Annual Reviews!
- 28th June, 9am GMT / 10am BST - ‘Nightlife of the stars of the brain: Astrocyte Ca2+ signaling helps to maintain uninterrupted slow wave sleep’ with Dr Laura Bojarskaite, University of Oslo.
Dr Laura Bojarskaite is a neuroscientist, currently working as a postdoc in Rune Enger lab at the University of Oslo. She researches astrocytes and their role in sleep and brain waste clearance.
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