3 years ago

Mitotic Chromosomes: Not So Silent After All

Mitotic Chromosomes: Not So Silent After All
H.T. Marc Timmers, C. Peter Verrijzer

Mitotic chromosome condensation is believed to be incompatible with transcription. Palozola et al. (2017) now report in Science that a transcription program is maintained during mitosis and that transcriptional re-activation at mitotic exit is geared to support cell growth rather than cell identity.

Publisher URL: http://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30815-8

DOI: 10.1016/j.devcel.2017.10.002

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