3 years ago

Interactions between sirtuins and fluorogenic small-molecule substrates offer insights into inhibitor design

Interactions between sirtuins and fluorogenic small-molecule substrates offer insights into inhibitor design
Zhu-Jun Yu, Qiang Chen, Shu Zhou, Kai Chen, Linna Cheng, Guo-Bo Li, Chengyong Wu, Sha Liu, Hua-Li Wang, Yuxi Wang, Yamei Yu
Biophysical and crystallographic analyses of small-molecule substrates with sirtuins provide thermodynamic insights and key pharmacophore features for inhibitor design.

Publisher URL: http://feeds.rsc.org/~r/rss/ra/~3/RPQDKUnYknY/C7RA05824A

DOI: 2017/RA/C7RA05824A

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