Join our third episode on 28th July at 10am BST / 9am GMT with Dr Roopesh Krishnankutty, University of Edinburgh. Sign up here to receive email reminders for this series.
What are we going to talk about in this episode?
The talk will present a discussion of the basics of mass spectrometry-based proteomics, different types of data acquisitions, basics of Mass Spectrometry (MS) data analysis, software used for downstream data processing, data enrichment analysis as well as visualizations for data interpretation. In addition, this presentation will give you an overview of how proteomics could be applied to cancer research. To explain the cancer application of proteomics, the conversation will focus on data obtained from a previously published research project.
Event slides can be found here.
- 20th July, 10am BST / 9am GMT - ‘A new method for the analysis of short-chain fatty acids (SCFA) and other polar metabolites in microbiome-related samples by ion-exchange chromatography-mass spectrometry (IC-MS)’ with Dr Mariya Misheva, University of Oxford
- 21st July, 4pm BST/ 3pm GMT - ‘Building a Versatile Intact Mass Toolkit to Improve Integrative Protein Structure Characterization for Drug Development and Basic Research’ with Dr Aaron Bailey, The University of Texas Medical Branch
- 28th July, 10am BST/9am GMT – ‘Mass Spectrometry-based bottom-up proteomics and its applications in cancer research: an overview’ with Dr Roopesh Krishnankutty, Senior Mass Spectrometry Researcher at the University of Edinburgh
- 2nd August, 10am BST/9am GMT – ‘Determining mass, why it is important and why it matters?’ with Dr Gillian Taylor - 2nd August 10am BST, Teesside University
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Dr Roopesh Krishnankutty holds a PhD in Biochemistry from Aix-Marseille University, France. He is a recipient of ‘Augur Prize’ for the best contributions to the PhD thesis as well as the Young Scientist Award in Biotechnology as a part of his PhD program. After his PhD Dr. Krishnankutty joined as a Postdoctoral fellow at the Complex Carbohydrate Research Center, University of Georgia, USA, where his research was on functional characterization of enzymes involved in plant cell wall biosynthesis using Mass Spectrometry and real-time NMR. He then moved to Lund University, Sweden for his second postdoc with a fellowship from Caryl Trygger Foundation, Stockholm where his research was focused on functional characterization of telomere binding proteins. Afterward, Dr. Krishnankutty moved to Weill Cornell Medical College in Qatar as a Postdoctoral Associate and worked in the Proteomics Core facility wherein his research was focused on characterization of membrane proteins using quantitative proteomics approach. Dr. Krishnankutty then took up the position as a Research Scientist at the interim Translational Research Institute (iTRI) of Hamad Medical Corporation in Qatar where in he established the proteomics core facility and was a scientific lead.
Early this year (Feb-2022) Dr. Krishnankutty moved to the UK and joined the Mass Spectrometry Facility at Institute of Genetics and Cancer (IGC), The University of Edinburgh, Scotland as a Senior Research Officer where in he leads the proteomics-based research projects of the core facility. Dr. Krishnankutty has published many articles in ISI journals and has authored and co-authored many book chapters. His research interests are mainly focused on protein characterization using Mass Spectrometry-based Proteomics approach. Dr. Krishnankutty is actively involved in developing novel proteomics-based workflows to apply this technology in cancer research
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