3 years ago

Alternative fluorophores designed for advanced molecular imaging

Alternative fluorophores designed for advanced molecular imaging
Fluorescent molecular imaging has advanced drastically over the last decade. With the development of high resolution microscopy techniques and the ability to visualize intracellular molecular events, there is a growing need for new fluorophores to accompany these fast-developing techniques. Therefore, there has been the substantial development of alternative fluorophores for single molecule detection and molecular imaging. These rationally designed fluorophores have infinite possibilities and novel fluorophores are constantly being produced for different applications. This review focused on the recent developments in novel fluorophores designed for molecular imaging and single molecule detection. Here within, single molecule imaging, smart fluorescent probes, two photon microscopy, Förster resonance energy transfer (FRET), and super resolution microscopy are discussed in detail.

Graphical abstract

A wide variety of alternative and novel fluorophores have been developed with wide-reaching applications in the fields of single molecule detection and molecular imaging.

Publisher URL: www.sciencedirect.com/science

DOI: S1359644616305049

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