3 years ago

Preparation of tetrazine-containing [2 + 1] complexes of 99mTc and in vivo targeting using bioorthogonal inverse electron demand Diels-Alder chemistry

Preparation of tetrazine-containing [2 + 1] complexes of 99mTc and in vivo targeting using bioorthogonal inverse electron demand Diels-Alder chemistry
Shannon Czorny, Tanya Miladinovic, Nancy Janzen, John F. Valliant, Robert G. Ungard, Abdolreza Yazdani, Gurmit Singh
A new 99mTc-labelled tetrazine for targeted imaging using bioorthogonal chemistry was developed and evaluated in vivo using a trans-cyclooctene derived bisphosphonate targeting regions of high bone turnover and bone lesions.

Publisher URL: http://feeds.rsc.org/~r/rss/DT/~3/FdUH7xFy-3A/C7DT01497J

DOI: 2017/DT/C7DT01497J

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