3 years ago

Bottom-up synthetic biology: modular design for making artificial platelets.

Sagardip Majumder, Allen P Liu
Engineering artificial cells to mimic one or multiple fundamental cell biological functions is an emerging area of synthetic biology. Reconstituting functional modules from biological components in vitro is a challenging yet an important essence of bottom-up synthetic biology. Here we describe the concept of building artificial platelets using bottom-up synthetic biology and the four functional modules that together could enable such an ambitious effort.

Publisher URL: http://doi.org/10.1088/1478-3975/aa9768

DOI: 10.1088/1478-3975/aa9768

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