During the last decade, extracellular vesicles (EVs) have emerged as a strong and attractive field of research. EVs are bi-layered nano-sized vesicles produced by most cell types with the capacity to package and deliver molecules such as RNAs and proteins to other cells, playing an important role in intercellular communication. Hence, due to their particular structure and composition, EVs have been envisaged as reservoirs of biomarkers for diagnosis, and as drug and gene delivery carriers for cell-free therapeutic approaches. 
From 28th November to 5th December, Researcher Live has invited outstanding experts to discuss their work in EV biology and their potential opportunities in biomedical research.
Join us on 28th November at 3pm for the first episode of this series with Dr María Yáñez-Mo from Autonomous University of Madrid.  

Episode summary:


Tetraspanins are a family of four transmembrane proteins that ensemble microdomains at the plasma membrane and membranes in the endosomal compartments. Our and others´ data suggest that they play an important role in EV cargo selection and have been widely used as EV markers. We have, on the one hand, used our tetraspanin-based tools for the development of different EV-related techniques, and on the other, studied their role in EV formation. These studies led us to describe a new role for tetraspanins as regulators of non-canonical mitophagy and, therefore, cell metabolic fitness.

Date and Time
Monday, November 28, 2022
03:00 pm - 04:00 pm GMT+0
Speakers Avatar Dr María Yáñez-Mo

Dr. Maria Yáñez earned her Ph.D. in Biochemistry and Molecular Biology from the Universidad Autónoma of Madrid (UAM). As a postdoctoral researcher, she was in charge of setting up the first confocal facility able to perform time-lapse microscopy in living cells in Spain. Since 2014, she is an associate professor in the department of molecular biology at the UAM. Her main research interest focuses on the biology and functionality of tetraspanins, important proteins involved in intracellular connections and in extracellular vesicles, and exosome’s biogenesis. Her scientific production accounts for more than 50 publications, and she is one of the most cited Spanish female scientists, as recently reported by the Spanish National Research Council. In 2011, she was a founder member of the International Society for Extracellular vesicles (ISEV) and, a year later, she was part of the founding committee of the Spanish Group of Research in Extracellular vesicles (GEIVEX).

DOI: u8SU49uaJt4sqqBbJYRg_prepost_1

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