Advanced Synthesis and Catalysis
Advanced Synthesis and Catalysis
5 years ago

Guanidinium Hydroiodide/Cumene Hydroperoxide-Mediated Intermolecular Oxidative Coupling Reaction of β–Ketoamides with Oxindoles

Guanidinium Hydroiodide/Cumene Hydroperoxide-Mediated Intermolecular Oxidative Coupling Reaction of β–Ketoamides with Oxindoles
Koji Yasui, Takanari Kato, Kazuo Nagasawa, Minami Odagi
The first catalytic intermolecular oxidative cross-coupling reaction between two different carbonyl compounds was achieved by using cumene hydroperoxide as an environmentally friendly, mild oxidant in the presence of a cyclic guanidinium hydroiodide derivative as a catalyst. Cross-coupling reaction between variouβ ketoamides and oxindoles took place smoothly, and the corresponding 1,4-dicarbonyl compounds were obtained in 80–99% yield.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/adsc.201700266

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.