Extracellular vesicles (EV) are bi-layered nano-sized vesicles that mediate intercellular communication and regulate multiple physiological and pathophysiological processes.
During the last years, EVs are becoming increasingly studied, not only to better understand cell communication but to be exploited as a new cell-free therapeutic approach.
Specifically, EV secreted by mesenchymal stromal cells can modulate inflammation and promote tissue healing, features that can be used to treat tissue injury such as myocardial infarction.
In this chapter, Dr Marta Monguió-Tortajada will summarize knowledge on EV therapeutic properties and strategies to foster their clinical use.
Join us on the 1st December at 3pm GMT for the third episode in our series "Emerging Biomedical Opportunities for Extracellular vesicles".
For more information about her work and the paper she authored, click here.
Event series program:
- Monday 28th November 3pm GMT: Studying tetraspanins in extracellular vesicles with Dr María Yañez-Mo, Autonomous University of Madrid
- Wednesday 30th November, 5.30pm GMT: Assessment of exRNAs for monitoring CNS-related injury and disease with Dr Kendall Van Keuren-Jensen, from the Translational Genomics Research Institute, Phoenix
- Thursday 1st December 3pm GMT: Therapeutic potential of extracellular vesicles with Dr Marta Moguió-Tortajada from Germans Trias i Pujol Research Institute in Barcelona
- Monday 5th December, 2pm GMT: Pharmacokinetics and biodistribution of extracellular vesicles after intravenous and intranasal administration in macaques with Dr Tom Driedonks from UMC Utrecht
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03:00 pm - 04:00 pm GMT+0
Dr Marta Monguió-Tortajada is a postdoctoral researcher working on extracellular vesicles (EV) and immunology in the context of cardiac inflammation and repair at the ICREC group led by Dr Bayes-Genis in the Germans Trias i Pujol Research Institute (IGTP) in Badalona, Spain. She was graduated in Biotechnology in 2012 (UAB) during which time she was granted a scholarship to attend the University of Technology of Sydney (2010). She did her MSc in Advanced Immunology (UB-UAB) at the group of Dr Borràs (IGTP), where she also continued with her Ph.D. She was granted the FI-DGR fellowship (AGAUR, Generalitat de Catalunya) to pursue her research in Immunology. Her work focused on the cellular and EV-based mechanisms of MSC for immunomodulation and tissue repair in the context of myocardial infarction, which she completed with summa cum laude (2018). Dr Monguió-Tortajada is an active member of ISEV (International Society of Extracellular Vesicles) and co-chairs the Taskforce for clinical translation of EV. She was a founding member of the Women in Science working group of the Can Ruti Campus (IGTP).
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