3 years ago

The use of a constant RBE=1.1 for proton radiotherapy is no longer appropriate.

Jakob Ödén, Colin G Orton, Paul M DeLuca
It is common practice to use a Relative Biological Effectiveness (RBE) of 1.1 when planning treatments and analyzing outcomes for proton therapy, even though it is known that the RBE varies across the spread-out Bragg peak. Since some claim that it is now possible to estimate RBE values throughout the treated volume, however, it has been suggested that this practice is no longer appropriate. This is the premise debated in this month's Point/Counterpoint. This article is protected by copyright. All rights reserved.

Publisher URL: http://doi.org/10.1002/mp.12646

DOI: 10.1002/mp.12646

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