4 years ago

Electrochemically driven reagent release from an electronic suture

Electrochemically driven reagent release from an electronic suture
Sutures loaded with growth factors or antimicrobials are commonplace but the release of the therapeutic agent is almost invariably achieved through passive release mechanisms. A gold microwire loaded with cellulose acetate phthalate encapsulated drug droplets is proposed as an alternative design approach. The release mechanism relies upon the imposition of a suitable reducing potential at the gold suture resulting in an increase in local pH and thereby induces the dissolution of the polymeric binder and releases the drug. The ability to actively control the dissolution-release processes could lay the foundations for smart suture design where more responsive/metered dosing could be achieved.

Publisher URL: www.sciencedirect.com/science

DOI: S1388248117301522

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.