Organic Letters
Organic Letters
5 years ago

Cp*Co(III)-Catalyzed Annulation of Carboxylic Acids with Alkynes

Cp*Co(III)-Catalyzed Annulation of Carboxylic Acids with Alkynes
Basker Sundararaju, Rajib Mandal
A new procedure for oxidative coupling of aromatic and acrylic acids with alkynes has been developed using abundant, nontoxic, and air stable Cp*Co(III) catalyst. The coupling involves initial cyclometalation via weak chelation-assisted C–H bond activation followed by alkyne coordination, insertion, and reductive elimination leading to diverse isocoumarins (α-pyranones) in good yields under mild conditions.

Publisher URL: http://dx.doi.org/10.1021/acs.orglett.7b00801

DOI: 10.1021/acs.orglett.7b00801

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.