3 years ago

Small RNAs Turn Over a New Leaf as Morphogens

Small RNAs Turn Over a New Leaf as Morphogens
Adrienne H.K. Roeder, Dana O. Robinson

In this issue of Developmental Cell, Skopelitis et al. (2017) demonstrate that sharp boundaries of gene expression can be created by threshold-based readout of mobile small RNA gradients. Support for this hypothesis comes from manipulation of small RNAs involved in top-bottom leaf patterning and from a novel synthetic biology approach.

Publisher URL: http://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30868-7

DOI: 10.1016/j.devcel.2017.10.025

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