3 years ago

Preparation, characterization and calcium release evaluation in vitro of casein phosphopeptides-soluble dietary fibers copolymers as calcium delivery system

Delivery systems based on food-grade biopolymers are of particular interest for food applications. Here, we introduce a new calcium delivery system with a high calcium-binding capacity and controlled calcium release. The system integrates casein phosphopeptides (CPP) with soluble dietary fibers (SDF). The physicochemical properties, calcium-binding capacities, controlled calcium release properties and formation mechanisms of the prepared copolymers with different mass ratios of CPP/SDF after thermal treatment were studied. The results showed that CPP-SDF copolymers significantly improved the calcium binding capacity (P < .05) from 11.63% to 46.8% and increased the calcium phosphate deposition time. The SDF in copolymers protected CPP from gastric enzyme hydrolysis so that most of the calcium was released under intestinal conditions in a controlled manner. Structural characterizations demonstrated different copolymer conformational states, and more calcium-binding sites existed within the CPP-SDF copolymers. The results show that copolymers based on food-sourced polymers are potential candidates for oral calcium delivery.

Publisher URL: www.sciencedirect.com/science

DOI: S0308814617316746

You might also like
Never Miss Important Research

Researcher is an app designed by academics, for academics. Create a personalised feed in two minutes.
Choose from over 15,000 academics journals covering ten research areas then let Researcher deliver you papers tailored to your interests each day.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.