Nanoscale
Nanoscale
5 years ago

Condition responsive nanoparticles for managing infection and inflammation in keratitis

Condition responsive nanoparticles for managing infection and inflammation in keratitis
Saad M. Ahsan, Ch. Mohan Rao
Anti-TLR4 conjugated GNPs (i) provide increased residence time at the corneal surface thereby decreasing the drug dosing frequency; (ii) minimize inflammation by inhibiting the downstream pathway of TLR4; (iii) act as an alternative substrate to proteolytic enzymes, minimizing the damage to the cornea while ketoconazole resolves the infection.

Publisher URL: http://feeds.rsc.org/~r/rss/NR/~3/Sm7WDzpf2QA/C7NR00922D

DOI: 2017/NR/C7NR00922D

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