3 years ago

Molecularly Imprinted Nanogels Acquire Stealth In Situ by Cloaking Themselves with Native Dysopsonic Proteins

Molecularly Imprinted Nanogels Acquire Stealth In Situ by Cloaking Themselves with Native Dysopsonic Proteins
Kazunori Kataoka, Reo Sasao, Yukiya Kitayama, Kazuko Toh, Takuya Yamada, Yu Matsumoto, Toshifumi Takeuchi
Cloaking nanogels with albumin yields stealth nanocarriers. In their Communication (DOI: 10.1002/anie.201700647), T. Takeuchi and co-workers describe the regulation of protein corona formation by molecular imprinting of polymeric nanogels. The nanogels acquire stealth in situ by capturing albumin after intravenous injection, forming an albumin-rich corona. As the nanogels accumulate passively in tumor tissue, this strategy may influence the development of drug nanocarriers for cancer therapy.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/anie.201704551

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.