3 years ago

Regulation of proteolysis in the Gram negative bacterial envelope.

Tracy L Raivio
Proteolysis is carefully regulated to prevent untimely destruction of critical proteins. In this issue of the Journal of Bacteriology, Kim and colleagues identify YjfN as a proteolytic regulator that stimulates the activity of the DegP/HtrA protease of Escherichia coli The suicide destruction and transcriptional regulation of YjfN limit its activity to conditions where there are likely to be many misfolded substrate proteins present.

Publisher URL: http://doi.org/10.1128/JB.00639-17

DOI: 10.1128/JB.00639-17

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