Proline-rich antimicrobial peptides targeting protein synthesis

5 years ago

Proline-rich antimicrobial peptides targeting protein synthesis

C. Axel Innis, Michael Graf, Gilles Guichard, Mario Mardirossian, Fabian Nguyen, Daniel N. Wilson, Marco Scocchi, A. Carolin Seefeldt

Proline-rich antimicrobial peptides (PrAMPs) bind within the exit tunnel of the ribosome and inhibit translation elongation. Structures of ribosome-bound PrAMPs reveal the interactions with ribosomal components and could pave the way for the development of novel peptide-based antimicrobial agents.

Publisher URL: http://feeds.rsc.org/~r/rss/NP/~3/x7tSn_Jzt5Y/C7NP00020K

DOI: 2017/NP/C7NP00020K

You might also like

Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.