4 years ago

Chemical constituents, antioxidant and gastrointestinal transit accelerating activities of dried fruit of Crataegus dahurica

Crataegus dahurica Koehne is an edible wild fruit mainly distributed in Northeast China. The purpose of this study was to elucidate the chemical constituents and investigate the bioactivities of dried fruit of C. dahurica methanol extract (CdME). Through various chromatographic methods, thirty-five compounds were isolated from CdME for the first time and their structures were identified on the basis of physicochemical properties and spectroscopic data. The main structural types of these compounds were triterpenoids and polyphenolics. Pharmacological experiments results showed that CdME had potently antioxidant capacity and ethyl acetate fraction was the active part with the greatest antioxidant activities. Moreover, CdME especially n-butanol fraction significantly accelerated the gastrointestinal transit in mice (acceleration rate: 78.5 ± 1.5% vs. 69.9 ± 3.2% at a dose of 250 mg/kg, compared to the control group, P < .01). On the basis of these results, C. dahurica may be considered as a good resource of antioxidants and digestion-improving agents.

Publisher URL: www.sciencedirect.com/science

DOI: S0308814617318149

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.