ChemCatChem
ChemCatChem
5 years ago

Organocatalytic Asymmetric Vinylogous Michael Reactions

Organocatalytic Asymmetric Vinylogous Michael Reactions
Zhiyong Jiang, Yanli Yin
Since R. C. Fuson formulated the principle of vinylogy, this platform has been extensively developed through combining diverse predominant chemical transformations. Among them, asymmetric vinylogous Michael reaction has been recognized as an efficient method to build chiral 1,7-dioxo C chains (1,9-dioxo C chains for bisvinylogous manifold) with diverse functional groups, which provides robust approaches to access numerous chiral compounds with pharmaceutical importance. In this review, the advances in the area of organocatalytic asymmetric vinylogous Michael reactions on the period from 2014 to nowadays are discussed, including the current scope, limitations of the transformations and applications in asymmetric synthesis of complex and valuable compounds. Asymmetric vinylogous Michael reaction has been recognized as an efficient method to build chiral 1,7- and 1,9-dioxo C chains with diverse functional groups, which provides robust approaches to numerous chiral multifunctional compounds with pharmaceutical importance. In this review, the advances of organocatalytic asymmetric vinylogous Michael reactions on the period from 2014 to nowadays are discussed.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/cctc.201700941

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.