Tetrahedron Letters
Tetrahedron Letters
4 years ago

Cu-catalyzed oxidation of indoles to isatins

Cu-catalyzed oxidation of indoles to isatins
The first example of Cu-catalyzed oxidation of indoles to isatin derivatives by the use of cheap aqueous tert-butyl peroxide as an oxidant was developed. This methodology is practically convenient and highly functional group tolerant, allowing a variety of indole derivatives to transform into the corresponding isatin derivatives in good yields.

Publisher URL: www.sciencedirect.com/science

DOI: S0040403917313503

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