4 years ago

Isoguanosine derivatives from the Northeastern Atlantic sponge Clathria (Microciona) strepsitoxa

Isoguanosine derivatives from the Northeastern Atlantic sponge Clathria (Microciona) strepsitoxa
After a chemical screening of subtidal sponges from the Northeastern Atlantic, Clathria (Microciona) strepsitoxa (Poecilosclerida: Microcionidae) was selected for deeper investigation. This first chemical study led to the identification of two new 8-oxoisoguanosine derivatives. The structure elucidation was performed after extensive analyses of spectroscopic (1D and 2D NMR) and HR-ESIMS data and no significant antimicrobial or cytotoxic activity was detected.

Publisher URL: www.sciencedirect.com/science

DOI: S0040403917313928

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