Chemical Communications
Chemical Communications
4 years ago

A continuous luminescence assay for monitoring kinase activity: signalling the ADP/ATP ratio using a discrete europium complex

A continuous luminescence assay for monitoring kinase activity: signalling the ADP/ATP ratio using a discrete europium complex
Romain Mailhot, Stephen J. Butler, Jonathan Parris, Sarah H. Hewitt
A stable Eu(III) complex is reported that binds reversibly to ATP and ADP, providing a ratiometric luminescent signal that enables the kinase-catalysed conversion of ATP to ADP to be monitored in real-time.

Publisher URL: http://feeds.rsc.org/~r/rss/CC/~3/H3oC0Xobg_g/C7CC05887J

DOI: 2017/CC/C7CC05887J

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