Chemistry - A European Journal
Chemistry - A European Journal
5 years ago

Frontispiece: Biosynthesis and Total Synthesis of Pyrronazol B: a Secondary Metabolite from Nannocystis pusilla

Frontispiece: Biosynthesis and Total Synthesis of Pyrronazol B: a Secondary Metabolite from Nannocystis pusilla
Swjatoslaw N. R. Witte, Markus Kalesse, Rolf Müller, Magalie N. E. Géraldy, Joachim J. Hug
Both the biosynthesis as well as the chemical synthesis of pyrronazol follow a modular approach starting with a pyrrole building block. This secondary metabolite was isolated from Nannocystis pusilla Ari7 and both routes utilize modular extensions to introduce an oxazole moiety and to generate the unsaturated lactone through ester condensation steps. For more information see the Full Paper by M. Kalesse et al. on page 15917 ff.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/chem.201786364

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