Clinical Cancer Research
Clinical Cancer Research
5 years ago

Drug repositioning meets precision in glioblastoma.

Wolfgang Wick, Tobias Kessler
Glioblastoma has a gigantic unmet medical need. Molecular knowledge has evolved substantially, including data on clonal selection with progression. Past trials for all-comers may have produced false negative results. Molecular precision at progression needs workup of new tissue and revisiting drugs with focus on brain tumor penetration may yield surprises.

Publisher URL: http://doi.org/10.1158/1078-0432.CCR-17-2989

DOI: 10.1158/1078-0432.CCR-17-2989

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